Table 1.

Clinical biochemistry parameters and serum insulin-like growth factor 1 (IGF-1) levels.

	Ctr	IF	Rot	Rot/IF
Glucose (mg/dl) 60–120	82.00 ± 13.49	78.83 ± 16.67	80.83 ± 19.34	87.0 ± 10.95
Creatinine (mg/dl) 0.50–1.20	0.82 ± 0.08	0.86 ± 0.22	0.78 ± 0.05	0.92 ± 0.18
Cholesterol (mg/dl) 50–120	71.00 ± 17.37	84.0 ± 20.71	77.66 ± 7.71	82.6 ± 12.52
Triglycerides (mg/dl) 80–200	85.33 ± 6.05	83.83 ± 2.14	88.17 ± 6.94	85.2 ± 3.35
AST (U/L) 20–250	54.17 ± 13.65	80.00 ± 40.48	49.00 ± 8.15	40.8 ± 16.51
Alanine transaminase (ALT) (U/L) 20–100	26.38 ± 4.48	24.48 ± 1.70	26.60 ± 4.06	26.54 ± 5.65
Creatine phospho-kinase (CPK) (U/L) 100–300	219.50 ± 61.08	162.00 ± 67.05	254.17 ± 67.62	234.4 ± 60.57
IGF-1 (pg/ml)	1005 ± 40	866 ± 30*	1100 ± 118	901 ± 32#

Mice were treated daily with rotenone (Rot) concomitant to normal feeding with control diet or intermittent fasting (IF, 24 h alternate-day fasting) for 28 days. Prior sacrifice, mice were starved for 2 h and blood was collected for clinical biochemistry analyses and for assessing IGF-1 levels (n = 6 each group, *p = 0.013, ^#p = 0.034 vs. Ctr).