Table 2.
Cardiorespiratory variables and arterial blood gases before and following bottle-feeding in full-term lambs.
| Control, n = 8 | nCPAP 6 cmH2O, n = 8 | HFNC 7 L/min, n = 8 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Before bottle-feeding | |||||||||||
| Heart rate (bpm) | 201 (175, 211) | 216 (193, 230) | 224 (195, 251) | ||||||||
| Respiratory rate (min−1) | 42 (36, 57) | 27 (24, 36)* | 42 (35, 54) | ||||||||
| SpO2 (%) | 95 (94, 95) | 95 (95, 97) | 96 (94, 98) | ||||||||
| PaO2 (mmHg) | 82 (74, 91) | 94 (83, 108)*,‡ | 88 (73, 94) | ||||||||
| PaCO2 (mmHg) | 40 (37, 41) | 42 (39, 45) | 40 (38, 43) | ||||||||
| pH | 7.45 (7.44, 7.46) | 7.44 (7.42, 7.45) | 7.45 (7.44, 7.46) | ||||||||
| 1 min after bottle-feeding | |||||||||||
| Heart rate (bpm) | 190 (173, 206) | 209 (192, 235) | 230 (193, 264) | ||||||||
| Respiratory rate (min−1) | 42 (35, 44) | 32 (26, 39) | 42 (34, 54) | ||||||||
| SpO2 (%) | 95 (95, 96) | 95 (93, 97) | 95 (92, 95) | ||||||||
| PaO2 (mmHg) | 91 (83, 96) | 98 (91, 108) | 83 (73, 97) | ||||||||
| PaCO2 (mmHg) | 40 (36, 42) | 39 (37, 40) | 40 (40, 43) | ||||||||
| pH | 7.43 (7.43, 7.45) | 7.43 (7.42, 7.44) | 7.44 (7.41, 7.44) | ||||||||
| 5 min after bottle-feeding | |||||||||||
| Heart rate (bpm) | 201 (177, 229) | 235 (214, 245) | 232 (190, 251) | ||||||||
| Respiratory rate (min−1) | 48 (41, 67) | 32 (29, 42)* | 36 (32, 44) | ||||||||
| SpO2 (%) | 95 (92, 96) | 93 (91, 96) | 94 (93, 95) | ||||||||
| PaO2 (mmHg) | 82 (76, 88) | 90 (78, 103)*,‡ | 77 (69, 100) | ||||||||
| PaCO2 (mmHg) | 41 (37, 42) | 40 (38, 42) | 40 (34, 41) | ||||||||
| pH | 7.43 (7.42, 7.45) | 7.43 (7.41, 7.44) | 7.44 (7.43, 7.45) | ||||||||
| 15 min after bottle-feeding | |||||||||||
| Heart rate (bpm) | 199 (180, 214) | 233 (218, 242) | 234 (196, 265) | ||||||||
| Respiratory rate (min−1) | 53 (45, 57) | 33 (29, 39)* | 42 (32, 65) | ||||||||
| SpO2 (%) | 95 (94, 96) | 95 (93, 96) | 92 (91, 95) | ||||||||
| PaO2 (mmHg) | 86 (82, 89) | 87 (82, 99) | 85 (64, 88) | ||||||||
| PaCO2 (mmHg) | 41 (40, 43) | 42 (40, 44) | 39 (37, 42) | ||||||||
| pH | 7.44 (7.43, 7.45) | 7.43 (7.41, 7.45) | 7.45 (7.44, 7.45) | ||||||||
Results are presented as median (Q1, Q3).
*p < 0.05 vs. control.
‡p < 0.05 vs. HFNC.
nCPAP, nasal continuous positive airway pressure 6 cmH2O; HFNC, high-flow nasal cannula 7 L/min; SpO2, hemoglobin saturation; PaO2, partial pressure of oxygen in arterial blood; PaCO2, partial pressure of carbon dioxide in arterial blood.