Table 7.

Effect of bis (diphenylacetato) cadmium (II) (DPAA), 1-(4-chlorobenzoyl)-3-(4-ferrocenylphenyl) urea (DPC1) and metformin on glycosylated hemoglobin A1C (HbA1C) in mice.

Groups	HbA1C Levels (%)
Non-Diabetic Control (Saline, 10 mL/Kg)	3.1 ± 0.05
Diabetic Control (Alloxan, 300 mg/Kg)	6.6 ± 0.11
Alloxan (300 mg/Kg) + DPAA (1 mg/Kg)	4.4 ± 0.10***
Alloxan (300 mg/Kg) + DPAA (5 mg/Kg)	3.6 ± 0.06***
Alloxan (300 mg/Kg) + DPAA (10 mg/Kg)	3.3 ± 0.12***
Alloxan (300 mg/Kg) + DPC1 (1 mg/Kg)	4.2 ± 0.07***
Alloxan (300 mg/Kg) + DPC1 (5 mg/Kg)	3.9 ± 0.05***
Alloxan (300 mg/Kg) + DPC1 (10 mg/Kg)	3.7 ± 0.18***
Alloxan (300 mg/Kg) + Metformin (500 mg/Kg)	3.4 ± 0.09***

Data expressed as mean ± SEM. Statistical analysis used one-way ANOVA, followed by post-hoc Tukey's test.

^***P < 0.001 comparison of the HbA1C levels of DPAA, DPC1 and metformin treated groups vs. diabetic control group. The sample size in each group comprised of five mice (n = 5).