Effect of AT-I on hippocampal NLRP3 inflammasome complex protein levels in chronic unpredictable mild stress-induced mice. Relative expression of (A) NLRP3, (B) ASC and (C) caspase-1, and (D) representative western blot images. Values are expressed as the mean ± standard deviation (n=6). ###P<0.001 compared with the control group; **P<0.01, ***P<0.001 compared with the model group. AT1/2/3, model mice treated with atractylenolide-I at 5, 10 or 20 mg/kg; FLU, model mice treated with fluoxetine; NLRP3, nucleotide binding and oligomerization domain-like receptor family pyrin domain-containing 3; ASC, apoptosis-associated speck-like protein.