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. 2018 Jan 21;24(3):371–378. doi: 10.3748/wjg.v24.i3.371

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©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

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Receiver operating characteristic analysis of probability after discriminant analysis. In the total nine genes, GPC3, ANXA1, FOS, SPAG9, CXCR4, and PFN1 genes entered the diagnosis formula. In the four genes, ANXA1, SPAG9, and PFN1 genes entered the formula. The probability was used for HCC detection. The AUC of the six selected genes was 0.926 and that of the three selected genes was 0.877. When the cutoff of the five selected genes was 0.628, the sensitivity and specificity were 82% and 89%, respectively.