Table 5.
Association of autoantibodies and prognosis of Kasai procedure with follow-up of 52 biliary atresia patients n (%)
| Parameter |
Anti-M2-3E |
ANA |
ANCA |
|||
| Positive, n = 17 | Negative, n = 35 | Positive, n = 8 | Negative, n = 44 | Positive, n = 29 | Negative, n = 23 | |
| TB, μmol/L | 105.5 ± 80.3 | 109.4 ± 106.8 | 41.6 ± 49.5 | 127.9 ± 135.0 | 133.0 ± 120.7 | 85.3 ± 66.2 |
| ALT, U/L | 184.1 ± 119.8 | 171.7 ± 121.4 | 127.9 ± 135.0 | 185.8 ± 115.7 | 171.46 ± 95.5 | 179.6 ± 140.3 |
| Occurrence of cholangitis | 9 (52.9) | 20 (57.1) | 5 (62.5) | 24 (54.5) | 24 (82.8)a | 5 (21.7)a |
Data are described as mean ± SD.
a
P < 0.05, r = 0.61; ANCA showed a positive correlation to the occurrence of postoperative cholangitis. TB is showed as a parameter of persistence of jaundice (TB > 34 μmol/L); ALT is showed as a parameter of acute liver injury (ALT > 35 U/L). ANCAs: Any positivity of ANCAs or specific ANCAs. ALT: Alanine aminotransferase; ANA: Anti-nuclear antibody; ANCA: Anti-neutrophil cytoplasmic antibody; BA: Biliary atresia; TB: Total bilirubin.