Table II.
Polymorphism | Cases, n (%) | Controls, n (%) | OR (95% CI) | P-value |
---|---|---|---|---|
rs4848320 | ||||
Codominant | ||||
CC | 26 (23.6) | 48 (40.0) | 1.00 | – |
CT | 60 (54.6) | 52 (43.3) | 2.13 (1.16–3.90) | 0.014 |
TT | 24 (21.8) | 20 (16.7) | 2.21 (1.03–4.74) | 0.041 |
Dominant | ||||
CC | 26 (23.6) | 48 (40.0) | 1.00 | – |
CT+TT | 84 (76.4) | 72 (60.0) | 2.15 (1.22–3.81) | 0.009 |
Recessive | ||||
CC+CT | 86 (78.2) | 100 (83.3) | 1.00 | – |
TT | 24 (21.8) | 20 (16.7) | 1.39 (0.72–2.70) | 0.322 |
Overdominant | ||||
CC+TT | 50 (45.4) | 68 (56.7) | 1.00 | – |
CT | 60 (54.6) | 52 (43.3) | 1.57 (0.93–2.64) | 0.090 |
Allele | ||||
C | 112 (50.9) | 148 (61.7) | 1.00 | – |
T | 108 (49.1) | 92 (38.3) | 1.55 (1.07–2.25) | 0.024 |
rs1110839 | ||||
Codominant | ||||
TT | 43 (39.1) | 54 (45.0) | 1.00 | – |
TG | 43 (39.1) | 34 (28.3) | 1.59 (0.87–2.90) | 0.132 |
GG | 24 (21.8) | 32 (26.7) | 0.94 (0.48–1.83) | 0.860 |
Dominant | ||||
TT | 43 (39.1) | 54 (45.0) | 1.00 | – |
TG+GG | 67 (60.9) | 66 (55.0) | 1.27 (0.75–2.16) | 0.365 |
Recessive | ||||
TT+TG | 86 (78.2) | 88 (73.3) | 1.00 | – |
GG | 24 (21.8) | 32 (26.7) | 0.77 (0.42–1.41) | 0.393 |
Overdominant | ||||
TT+GG | 67 (60.9) | 86 (71.7) | 1.00 | – |
TG | 43 (39.1) | 34 (28.3) | 1.62 (0.93–2.82) | 0.085 |
Allele | ||||
T | 129 (58.6) | 142 (59.2) | 1.00 | – |
G | 91 (60.4) | 98 (40.8) | 1.02 (0.70–1.48) | 0.924 |
rs6726151 | ||||
Codominant | ||||
GG | 40 (36.3) | 56 (46.6) | 1.00 | – |
GT | 63 (57.3) | 47 (39.2) | 1.88 (1.08–3.27) | 0.036 |
TT | 7 (6.4) | 17 (14.2) | 0.58 (0.22–1.52) | 0.576 |
Dominant | ||||
GG | 40 (36.4) | 56 (46.6) | 1.00 | – |
GT+TT | 70 (63.7) | 64 (53.4) | 1.53 (0.90–2.60) | 0.141 |
Recessive | ||||
GG+GT | 103 (93.6) | 103 (85.8) | 1.00 | – |
TT | 7 (6.4) | 17 (14.2) | 0.41 (0.16–1.04) | 0.082 |
Overdominant | ||||
GG+TT | 47 (42.7) | 73 (60.8) | 1.00 | – |
GT | 63 (57.3) | 47 (39.2) | 2.08 (1.23–3.53) | 0.008 |
Allele | ||||
G | 143 (65.0) | 159 (72.3) | 1.00 | – |
T | 77 (35.0) | 81 (27.7) | 1.06 (0.72–1.55) | 0.844 |
OR, odds ratio; CI, confidence interval.