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Antinociceptive effect of A in the tail flick test in rats. Tail flick latency in rats was recorded following treatment with different doses of A (42, 84 and 168 mg/kg, i.p.). Latency was assessed at 15, 30, 45, 60 and 75 min after drug administration. Data are expressed as the mean ± standard error of the mean, n=8–9 per group. *P<0.05 vs. N.S. control at 15 min. A, acetaminophen; N.S., normal saline; i.p., intraperitoneal injection.
