Table 2.
Inhibition of P-gp-mediated Rhodamine 123 efflux of selected quinolines in comparison to verapamil at the concentration of 10 μM
Compound | P-gp inhibition fold |
---|---|
4b | 0.31 |
6b | 0.75 |
Verapamil | 1 |
5a | 1.375 |
5b | 2.175 |
Inhibition of P-gp-mediated Rhodamine 123 efflux of selected quinolines in comparison to verapamil at the concentration of 10 μM
Compound | P-gp inhibition fold |
---|---|
4b | 0.31 |
6b | 0.75 |
Verapamil | 1 |
5a | 1.375 |
5b | 2.175 |