Relative protein expression levels of PTEN, PI3K and AKT in the rat tissues (in vivo experiment). A rat model of sepsis was established (referred to as the LPS group), and model rats were then treated with miR-30a-3p (referred to as the miRNA group). #P<0.05 vs. the NC group; ***P<0.05 vs. the LPS group. LPS, lipopolysaccharide; miR, microRNA; NC, normal control; PTEN, phosphatase and tensin homolog; PI3K, phosphoinositide 3-kinase; AKT, protein kinase B.