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. 2017 Dec 1;15(2):1269–1276. doi: 10.3892/etm.2017.5588

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Copyright: © Zhang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — Paclitaxel treatment inhibits breast cancer cells growth in MCF-bearing mice in vivo. (A) Paclitaxel treatment significantly inhibits breast tumor growth compared to control group. (B) Paclitaxel treatment significantly increases numbers of apoptotic cells in tumor tissues. (C) Paclitaxel treatment downregulates expression levels Aurora and cofilin-1 in tumor tissues. (D) Paclitaxel treatment decreases Aurora and cofilin-1 activity in tumor tissues. All data were expressed as mean ± SD of three independent experiments using Student's t-test or one-way ANOVA or Kruskal-Wallis test. **P<0.01 vs control group.