Table 2.
Correlation coefficients between IL-18 and clinical, metabolic and inflammatory parameters.
| T2D (n = 76) | LADA (n = 24) | Controls (n = 14) | T2D (n = 28)# | LADA (n = 20)# | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| r | P | r | P | r | P | r | P | r | P | |
| BMI (kg/m2) | 0.015 | 0.897 | 0.210 | 0.325 | 0.004 | 0.988 | 0.240 | 0.219 | 0.328 | 0.158 |
| WC (cm) | 0.073 | 0.532 | 0.297 | 0.169 | 0.064 | 0.827 | 0.219 | 0.262 | 0.379 | 0.110 |
| SBP (mmHg) | −0.037 | 0.749 | 0.289 | 0.171 | 0.527 | 0.053 | 0.172 | 0.382 | 0.228 | 0.333 |
| DBP (mmHg) | −0.094 | 0.418 | 0.133 | 0.535 | 0.507 | 0.064 | 0.080 | 0.687 | 0.067 | 0.780 |
| FPG (mmol/L) | 0.075 | 0.530 | −0.098 | 0.655 | 0.483 | 0.094 | 0.152 | 0.449 | −0.261 | 0.280 |
| PPG (mmol/L) | 0.244 | 0.043 | 0.027 | 0.907 | – | – | 0.290 | 0.151 | −0.001 | 0.997 |
| HbA1c (%) | 0.007 | 0.956 | 0.168 | 0.434 | – | – | 0.059 | 0.771 | 0.157 | 0.508 |
| LDL-C (mmol/L) | −0.141 | 0.251 | 0.134 | 0.563 | −0.500 | 0.667 | −0.099 | 0.645 | 0.059 | 0.823 |
| HDL-C (mmol/L) | −0.377 | 0.001 | −0.392 | 0.079 | 0.500 | 0.667 | −0.464 | 0.019 | −0.412 | 0.101 |
| TG (mmol/L) | 0.072 | 0.546 | 0.301 | 0.154 | −0.172 | 0.557 | 0.044 | 0.829 | 0.281 | 0.231 |
| hs-CRP (mg/L) | 0.427 | 0.001 | 0.113 | 0.832 | −0.241 | 0.406 | 0.493 | 0.017 | 0.128 | 0.591 |
| IL-6 (pg/mL) | 0.398 | <0.001 | −0.131 | 0.541 | −0.241 | 0.406 | 0.408 | 0.035 | 0.020 | 0.934 |
#Correlations within groups with BMI-matched participants.
BMI, body mass index; DBP, diastolic blood pressure; FPG, fasting plasma glucose; HDL-C, high density lipoprotein cholesterol; Hs-CRP, high-sensitivity C-reactive protein; IL-6, interleukin 6; IL-18, interleukin-18; LADA, latent autoimmune diabetes of the adults; LDL-C, low density lipoprotein cholesterol; PPG, postprandial plasma glucose; SBP, systolic blood pressure; T2D, type 2 diabetes; TG, triglycerides; WC, waist circumference.
This work is licensed under a