. Author manuscript; available in PMC: 2018 Jan 22.

Published in final edited form as: Transl Stroke Res. 2013 Nov 16;5(1):69–78. doi: 10.1007/s12975-013-0305-y

Table 1.

Electrophysiological and pharmacological properties of homomeric ASIC

Gene	Protein	Alternative name	pH₅₀ activation	Non-proton ligand	Inhibitor
ACCN2	ASIC1a	ASICα BNaC2α	6.2–6.8	MitTx	Amiloride PcTx1 Mambalgins PhcrTx1 Zn²⁺
ACCN2	ASIC1b	ASICβ BNaC2β	5.9	MitTx	Amiloride Mambalgins PhcrTx1 Zn²⁺
ACCN1	ASIC2a	BNaC1α BNC1a	4.4	MitTx	Amiloride
ACCN1	ASIC2b	BNaC1β MDEG2	N/A	ND	N/A
ACCN3	ASIC3	DRASIC TNaC	6.2–6.7	GMQ MitTx	Amiloride APETx2 Zn²⁺
ACCN4	ASIC4	SPASIC	N/A	ND	N/A

N/A not applicable, ND not determined