Table 3.
Chemical data used for input into the cancer MCDA.
| Toxicity | Occurrence (% of FracFocus 1.0 Disclosures)a |
Physicochemical properties | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
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| CASRN | Chemical name | OSF (per mg/kg-day) | Source of OSF | National | TX | PA | ND | LogKOW | LogKOC | Aqueous solubility (mg/l) | Henry's law constant | Half-life in water |
| 91-22-5 | Quinoline | 3 | IRIS | 0.02% | 0.04% | 2.03 | 3.1 | 1711 | 1.67E-06 | 15 | ||
| 111-44-4 | Bis(2-chloroethyl) ether | 1.1 | IRIS | 0.7% | 0.9% | 1% | 1.29 | 1.88 | 6435 | 1.70E-05 | 37.5 | |
| 79-06-1 | Acrylamide | 0.5 | IRIS | 1% | 2% | 1% | 1% | −0.67 | 0.755 | 504,000 | 1.70E-09 | 15 |
| 100-44-7 | Benzyl chloride | 0.17 | IRIS | 6% | 7% | 5% | 0.8% | 2.3 | 2.649 | 1030 | 4.12E-04 | 15 |
| 123-91-1 | 1,4-Dioxane | 0.1 | IRIS | 0.3% | 0.5% | 0.8% | −0.27 | 0.421 | 213,900 | 4.80E-06 | 15 | |
| 71-43-2 | Benzene | 0.055 | IRIS | 0.006% | 0.01% | 2.13 | 1.75 | 2000 | 5.55E-03 | 37.5 | ||
| 542-75-6 | 1,3-Dichloropropene | 0.05 | IRIS | 0.02% | 2.04 | 1.82 | 1994 | 3.55E-03 | 37.5 | |||
| 106-89-8 | Epichlorohydrin | 0.0099 | IRIS | 1% | 0.2% | 0.08% | 0.45 | 1 | 50,630 | 3.04E-05 | 15 | |
| 62-53-3 | Aniline | 0.0057 | IRIS | 0.02% | 0.05% | 0.9 | 1.6 | 20,820 | 2.02E-06 | 15 | ||
| 75-09-2 | Dichloromethane | 0.002 | IRIS | 0.02% | 1.25 | 1.44 | 10,950 | 3.25E-03 | 37.5 | |||
a
The cancer MCDA was only performed using the nationwide dataset. State-specific frequency of use for these chemicals is provided here for reference only.