Table 6.
Type | % of cases | Histologically Mimicks | Description |
---|---|---|---|
A | 47–82% | Hodgkin lymphoma Transformed MF |
• Large Reed-Sternberg-like atypical lymphocytes • Wedge-shaped heterogeneous infiltrate with lymphocytes, neutrophils, eosinophils and histiocytes |
B | 4–17% | MF | • Epidermotropic band-like infiltrate • Small irregular lymphocytes • Cerebriform nuclei |
C | 7–22% | ALCL | • Sheets or clustered infiltrate • Large atypical lymphocytes • Few inflammatory cells |
D | ~8% | Primary cutaneous aggressive CD8+ cytotoxic T-cell lymphoma (TCL), PLC/PLEVA Pagetoid reticulosis Cutaneous gamma/delta TCL |
• Epidermotrophic infiltrate • CD8+ • Small to medium atypical lymphocytes |
E | ~0.6% | Angiocentric: Extranodal NK/T-cell lymphoma, nasal type Cutaneous gamma/delta TCL ALCL variant with angiocentric and/or angiodestructive growth |
• Small- to medium-sized lymphocytes • Angiocentric: CD8+ infiltrating walls of small to medium-sized vessels • Vasculitis: fibrin, thromboses and extravasation of red blood cells |
F58 | 5–10% | Folliculotropic: Folliculotropic MF Pseudolymphoma Connective tissue diseases |
• Perifollicular infiltrate • Medium to large lymphoid cells • Follicular mucinosis • Neutrophils within infundibula |
Mixed | 4–9% | • More than 1 histological type in the same patient or lesion |