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. Author manuscript; available in PMC: 2018 Aug 19.
Published in final edited form as: Ann Neurol. 2017 Aug 19;82(2):247–258. doi: 10.1002/ana.24996

Figure 1. Digital image analysis of cerebral tau pathology.

Figure 1

Representative photomicrographs depict raw images (top) and digital image analysis thresholding quantification (%AO; bottom- red/orange/yellow overlay) of tau pathology in the mid-frontal cortex for A–B) AD, C–D) FTLD-Tau and E–F) FTLD-TDP with coincident AD pathology. There is higher overall and GM burden of cerebral tau pathology in AD compared to FTLD-Tau and FTLD-TDP, while FTLD-Tau has higher white-matter tau pathology compared to both groups.