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. 2017 Dec 18;115(1):E34–E43. doi: 10.1073/pnas.1713526115

Fig. 2.

Fig. 2.

Scheme of the design of the anti-lysozyme Goldbody. (A) Structure of cAb-Lys3 (green, with the CDR3 loop shown in magenta) in complex with HEWL (cyan) [Protein Data Bank (PDB) ID code 1MEL]. (B) Model of the anti-lysozyme Goldbody (with the grafted peptide loop shown in magenta) in complex with HEWL (cyan); for clarity, only one peptide is shown on the AuNP. (C) Structure of HEWL (cyan) in complex with its inhibitor Tri-NAG (shown as sticks) (PDB ID code 1HEW). (D) Sequences of the CDR3 fragment (100 to 112) of HEWL and the three designed peptides.