Table 2.

Univariate and multivariate analyses of related factors for predicting the overall survival of patients with bladder cancer in a Cox proportional hazards model

Variables	Univariate analysis			Multivariate analysis
	HR	95% CI	P	HR	95% CI	P
Sex
Male/female	1.73	0.72–4.17	0.22	1.79	0.65–4.84	0.33
Age
>65 years/≤65 years	1.60	0.77–3.34	0.21	1.34	0.63–2.88	0.45
Tumor grade
G II + III/G I	8.58	2.94–25.03	<0.01	11.56	3.37–39.58	<0.01
Clinical tumor stage
T2 + T3/Ta + T1	3.36	1.50–7.56	<0.01	1.23	0.42–3.60	0.70
Size
<3 cm/≥3 cm	0.99	0.51–1.90	0.97	0.59	0.25–1.39	0.22
Multiplicity
Multiple/single	0.59	0.30–1.14	0.12	0.63	0.31–1.29	0.21
Smoking
Yes/no	1.09	0.55–2.14	0.81	0.95	0.33–2.74	0.93
Drinking
Yes/no	0.88	0.43–1.83	0.74	0.77	0.27–2.25	0.64
TIP30 expression
Strong/weak	0.25	0.12–0.53	<0.01	0.29	0.10–0.81	0.02

HR: Hazard ratio; CI: Confidence interval; TIP30: Tat-interacting protein 30.