Figure 5.

Concentration of caspase-8 in breast cancer MCF-7 cells following 24 h incubation with anti-MUC1 (10 and 20 µg/ml), Pt12 (10 and 20 µM), Pt12 + anti-MUC1 (10 µM + 10 µg/ml and 20 µM + 10 µg/ml), cisplatin (10 and 20 µM), cisplatin + anti-MUC1 (10 µM + 10 µg/ml and 20 µM + 10 µg/ml). The results are representative of data from 3 independent experiments. Data presented as the mean ± standard deviation. *P<0.05 and ***P<0.001, as indicated. MUC1, mucin 1; Pt12, platinum(II) complex; ns, not significant.