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. 2017 Dec 5;15(2):1673–1679. doi: 10.3892/ol.2017.7524

Figure 3.

Figure 3.

Overexpression of miR-370 reduces colon tumor growth in vivo. (A) qPCR analysis of miR-370 expression in SW620 cells that stably transfected with miR-370 and miR-NC, n=3; **P<0.01, compared with miR-NC cells. (B) Representative macroscopic findings of colon tumors. (C) Tumor volume after injection of 5×106 miR-NC or miR-370 SW620 cells into nude mice. n=5; *P<0.05; **P<0.01, compared with miR-NC group. (D) End-stage weight after injection of 5×106 miR-NC or miR-370 SW620 cells into nude mice. n=5; **P<0.01, compared with miR-NC group. (E) TUNEL analysis of apoptosis cells in miR-NC and miR-370 xenograft tumors, n=3; **P<0.01, compared with miR-NC group. miR, microRNA; qPCR, quantitative real-time polymerase chain reaction.