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. 2017 Nov 29;15(2):1949–1954. doi: 10.3892/ol.2017.7502

Figure 7.

Figure 7.

Effect of dihydroartemisinin on phosphorylation of JAK2 and STAT3 in CRC cells. (A) The effects of dihydroartemisinin on phosphorylation of JAK2 and STAT3 were assessed using western blot analysis. (B) Quantification of phosphorylation of JAK2 in HCT116 cells revealed a significant dose-dependent decrease following treatment with dihydroartemisinin. (C) Quantification of the phosphorylation of STAT3 in CRC cells revealed a significant dose-dependent decrease following treatment with dihydroartemisinin. **P<0.01 compared with the 0 µM dihydroartemisinin group. p-JAK2, phosphorylated Janus kinase 2; p-STAT3, phosphorylated signal transducer and activator of transcription 3.