Fig. 1.
Germ-line expression of GnasR201H causes embryonic lethality. (A) Lateral view of E10.5 and E12.5 littermate embryos with the indicated genotypes. (B and D) Representative images of whole-mount in situ hybridization performed with E9.5 embryos. (C and E) qRT-PCR analysis of the indicated gene expression from RNA isolated from whole embryos at E9.5. *P < 0.05; data are presented as mean ± SD. (Scale bars, 100 mm.)