Fig. 5.

Ephx2 promoter binding activity of transcription factors including SP1 (A and B), AP-1 (A and C), and NF-κB (A and D) in mouse arteries (A) and human 293 cells (B–D) in control conditions and in the presence of E₂, E₂ pus ICI, and E₂ plus Decitabine (Decit), respectively. *Significant difference from males (A); and from their controls and E₂ with ICI, respectively (B–D) (n = 5–8 for each group).