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. 2017 Dec 8;15(2):2287–2295. doi: 10.3892/ol.2017.7566

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Copyright: © Yang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — The expression and intracellular localization of β-catenin, LGR5 and GATA6 in a normal mucosa-adenoma-adenocarcinoma sequence. (A) Immunolabeling patterns and (B) quantitative analysis of β-catenin; (C) immunolabeling patterns and (D) quantitative analysis of LGR5; and (E) immunolabeling and (F) quantitative analysis of GATA6 in representative colorectal tissues, including normal mucosa, adenomas and adenocarcinomas obtained from the same patient. Scale bar=50 µm. *P<0.05, **P<0.01. LGR5, leucine-rich repeat-containing G protein-coupled receptor 5; GATA6, GATA-binding factor 6.