Table V.
β-catenin, LGR5 and GATA6 expression in adenoma stratified by histological grade of dysplasia.
| Cell membrane β-catenin | Nuclear β-catenin | LGR5 | Cytoplasmic GATA6 | Nuclear GATA6 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dysplasia | n | Median (IQR) | χ2 | n | Median (IQR) | χ2 | n | Median (IQR) | χ2 | n | Median (IQR) | χ2 | n | Median (IQR) | χ2 |
| Mild | 27 | 8 (2) | 2.17 | 27 | 4 (3) | 4.33a | 24 | 4 (7) | 0.46 | 27 | 0 (4) | 0.02 | 27 | 0 (3) | 0.57 |
| Moderate/severe | 29 | 7 (6) | 29 | 2 (3) | 22 | 4 (4) | 29 | 1 (3) | 29 | 0 (1) | |||||
a
P<0.05. Statistical analyses were performed using a Wilcoxon signed-rank test. LGR5, leucine-rich repeat-containing G protein-coupled receptor 5; GATA6, GATA-binding factor 6; IQR, interquartile range.