Table VII.
β-catenin, LGR5 and GATA6 expression in different invasive depth of colorectal adenocarcinoma.
| Cell membrane β-catenin | Nuclear β-catenin | LGR5 | Cytoplasmic GATA6 | Nuclear GATA6 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Parameters | n | Median (IQR) | χ2 | n | Median (IQR) | χ2 | n | Median (IQR) | χ2 | n | Median (IQR) | χ2 | n | Median (IQR) | χ2 |
| Mucosa | 28 | 4 (7) | 1.63 | 28 | 2 (7) | 8.23a | 14 | 7 (4) | 1.28 | 8 | 1 (4) | 3.79 | 8 | 2 (4) | 6.41 |
| Submucosa | 45 | 4 (4) | 45 | 2 (4) | 29 | 4 (3) | 29 | 1 (2) | 29 | 0 (1) | |||||
| Muscularis | 53 | 4 (6) | 53 | 3 (5) | 36 | 6 (4) | 42 | 2 (4) | 42 | 0 (1) | |||||
| Serosa | 10 | 2 (7) | 10 | 6 (9) | 7 | 4 (3) | 4 | 4 (6) | 4 | 0 (0) | |||||
a
P<0.05. Statistical analyses were performed using a Kruskal-Wallis test followed by the Steel-Dwass method. pTNM, pathological tumor-node-metastasis; LGR5, leucine-rich repeat-containing G protein-coupled receptor 5; GATA6, GATA-binding factor 6; IQR, interquartile range.