Fig. 4.

Reporter-based transcriptional activity of the FoxP3 mutants. EL4 T cells were transfected with EV, mutant, or WT FoxP3 together with the luciferase reporter plasmids described in Fig. S3 (8xFKRE, Top; Il2pro, Bottom). Data from two independent experiments are shown as mean ± SD (numeric values are in Dataset S3).