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. 2017 Dec 8;15(2):2236–2244. doi: 10.3892/ol.2017.7574

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Copyright: © Zuo et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — mRNA expression of IL-6, gp130, JAK1 and STAT3 in human gastric cancer tissues. (A) The mRNA expression of IL-6 in tumor tissues from patients at different T stages were significantly higher compared with adjacent non-tumor tissues (n=15). However, there were no significant differences in IL-6 expression between T1/T2 (n=23) and T3/T4 (n=39). (B) The mRNA expression of gp130 in tumor tissues of different T stages were significantly higher compared with adjacent non-tumor tissues (n=15). However, there were no significant differences in gp130 expression between T1/T2 (n=23) and T3/T4 (n=39). (C) The mRNA expression of JAK1 in tissues from patients with tumors at T3/T4 stages (n=39) was significantly increased compared with the expression in tumor tissues at T1/T2 stages (n=23), which were both significantly higher compared with adjacent non-tumor tissues (n=15). (D) The mRNA expression of STAT3 in tumor tissues at T3/T4 stages (n=39) was significantly increased compared with the expression in tumor tissues at T1/T2 stages (n=23), which were both significantly higher compared with adjacent non-tumor tissues (n=15). Values are expressed as the mean ± standard deviation. *P<0.05. gp130, interleukin 6 signal transducer; IL-6, interleukin-6; JAK1, Janus kinase 1; STAT3, signal transducer and activator of transcription 3.