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. 2017 Dec 8;15(2):2236–2244. doi: 10.3892/ol.2017.7574

Figure 5.

Figure 5.

Binding of STAT3 to promoter region in the HAMP gene in human gastric cancer. The binding affinity of STAT3 to the promoter region of HAMP gene in tumor tissue at T3/T4 stages (n=39) was significantly increased compared with T1/T2 stages (n=23), which were both significantly increased compared with adjacent non-tumor tissues (n=15). Values are expressed as the mean ± standard deviation. *P<0.05. HAMP, hepcidin antimicrobial peptide; STAT3, signal transducer and activator of transcription 3.