Figure 3.

Slower recovery in MEK1DD mutant mice vs controls, 1 month postinjury. A, Beam test was used to assess balance and motor coordination after injury. B, C, Rotarod test (B) and toe-spreading reflex test (C) confirmed deficits in motor function in MEK1DD mutant mice. C, Representative photographs of the toe spreading from day 13 postinjury are shown. D, Pin-prick test was used to analyze recovery in sensory functions. n = 11 mice. All tests were analyzed with two-way repeated-measures ANOVA; Sidak's multiple-comparison test apart from the rotarod test in which two-tailed unpaired t test was used. *p < 0.05, **p < 0.005, ***p < 0.001. Error bars indicate SEM.