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. 2017 Dec 5;15(2):1861–1868. doi: 10.3892/ol.2017.7520

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Figure 1. — FAM83H-AS1 and Notch1 were upregulated in CRC tissues and cell lines. (A) The levels of FAM83H-AS1, Notch1 and Hes1 in CRC tissues and the corresponding normal tissues were measured by RT-qPCR. (B) The correlation of FAM83H-AS1 with Notch1 and Hes1 was analyzed by Spearman's correlation analysis. (C) The levels of FAM83H-AS1, Notch1 and Hes1 were also determined by RT-qPCR in four human colonic cancer cell lines including SW480, LοVο, HCT116, HT29, and the human colonic epithelial cell HCoEpiC (control). Data are presented as the mean ± standard deviation of at least three independent experiments. **P<0.01 vs. control group. FAM83H-AS1, FAM83H antisense RNA 1 (head to head); CRC, colorectal carcinoma; RT-qPCR, reverse transcription-quantitative polymerase chain reaction; Hes1, Hes family basic-helix-loop-helix transcription factor 1.