Fig. 1. Clear group separation of blood transcript profiles.
Blood total RNAs from female patients with late-stage AD (n=9) and matched healthy control (n=10) were assayed by genome-wide gene expression microarrays using 60,000 probes. Array data were analyzed by unsupervised hierarchical cluster analysis. Values at branches are approximately unbiased (AU) p-values (left), bootstrap probability (BP) estimates (right) and cluster distance labels (bottom). Clusters with AU >95 were considered significant. AD1–9: AD patients; C1–10: healthy controls.