Figure 1.
Study design and therapy regimens. Stratification factors were Eastern Co-operative Oncology Group (ECOG) performance score (0–1 vs. 2) and blood blast level (<1 vs. ≥1×109/L). Randomization in the lenalidomide regime was suspended 11th September 2013 and permanently closed on 15th April 2014 as per Amendment 2 because of the high rate of discontinuation of the study treatment in subjects receiving high-dose continuous lenalidomide. AML: acute myeloid leukemia; PO: per oral administration; SC: subcutaneous injection; SPM: secondary primary malignancies.