Table III.
Correlation between CRLS1 and tumor clinical characteristics of patients with non-small cell lung cancer.
| Characteristic | Cases low (n) | Cases high (n) | HR (95% CI) | P-value |
|---|---|---|---|---|
| Stage | ||||
| I | 224 | 225 | 0.36 (0.26–0.51) | 2.7E-09 |
| II | 80 | 81 | 0.69 (0.43–1.09) | 0.11 |
| III | 22 | 22 | 0.54 (0.27–1.09) | 0.08 |
| Topography | ||||
| I | 112 | 112 | 0.63 (0.42–0.94) | 0.023 |
| II | 95 | 95 | 0.81 (0.55–1.17) | 0.26 |
| III | 14 | 15 | 1.06 (0.47–2.38) | 0.89 |
| Lymph node status | ||||
| N0 | 162 | 162 | 0.72 (0.52–0.98) | 0.037 |
| N1 | 51 | 51 | 0.81 (0.49–1.34) | 0.42 |
| N2 | 16 | 16 | 0.56 (0.27–1.2) | 0.13 |
| Metastasis | ||||
| M0 | 231 | 231 | 0.69 (0.54–0.89) | 0.0037 |
| M1 | – | – | – | – |
| Smoking status | ||||
| Never Smoked | 151 | 149 | 0.51 (0.33–0.78) | 0.0018 |
| Smoked | 70 | 71 | 0.33 (0.13–0.83) | 0.014 |
| Sex | ||||
| Male | 330 | 329 | 0.54 (0.44–0.67) | 8.7E-09 |
| Female | 189 | 186 | 0.45 (0.31–0.65) | 8.6E-06 |
| Chemotherapy | ||||
| Yes | 17 | 17 | 0.41 (0.12–1.34) | 0.13 |
| No | 10 | 10 | 3.94 (0.46–33.95) | 0.18 |
CRLS1, cardiolipin synthase 1.