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. 2017 Dec 13;15(2):2459–2464. doi: 10.3892/ol.2017.7610

Figure 6.

Figure 6.

10-Hydroxycamptothecin activates the p53 and PARP-1 signaling pathway of human osteosarcoma cells. p53 protein expression was analyzed using (A) western blot analysis with (B) quantification of p53 expression and (C) quantification of PARP-1 expression. **P<0.01 vs. 0 nM. PARP-1, polymerase-1.