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. 2017 Dec 8;15(2):2501–2507. doi: 10.3892/ol.2017.7547

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Figure 2. — Degree and cellular distribution of CXCL12 and CXCR4 expression in glioma tissues. (A-D) CXCL12 expression in vascular endothelial cells (black arrow) and in tumor cells (red arrow). (A) CXCL12 expression in glomeruloid vessels (magnification, ×200). (B) CXCL12 expression in the non-glomerular vessels of the peritumoral edema area (magnification, ×200). (C) CXCL12 is expressed in vascular endothelial cells of the surrounding necrotic area (magnification, ×200). (D) CXCL12 expression in tumor cells (magnification, ×200). (E-H) CXCR4 expression in tumor cells (red arrow) and endothelial cells (black arrows). (E) CXCR4 expression in tumor cells (magnification, ×200). (F) CXCR4 expression in perivascular tumor cells of the peritumoral edema area (magnification, 400). (G) CXCR4 expression in tumor cells in the surrounding necrotic area (magnification, ×200). (H) CXCR4 expression in glomeruloid vessels (magnification, ×200). CXCR4, C-X-C receptor 4; CXCL12, CXC-motif-chemokine 12.