Table 3. Intra- and intergroup comparisons of microbiological parameters (mean ± SD or median, IQ score at days 0 and 270.
| Variable | Time point | Treatment group | p- value** | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Probiotic group (n=16) | Antibiotic group (n=16) | Placebo group (n=15) | For mean | For delta | |||||
| Mean ± SD | Delta ± SD | Mean ± SD | Delta ± SD | Mean ± SD | Delta ± SD | ||||
| % P. gingivalis | |||||||||
| Day 0 | 14.2 ± 17.6 | -13.1 ± 18.6 | 17.8 ± 19.3 | -15.6 ± 17.9 | 14.7 ± 15.7 | -14.4 ± 15.9 | 0.97738 | 0.99028 | |
| Day 270 | 1.1 ± 2.6† | 2.1 ± 6.6† | 0.3 ± 1.0† | 0.5882 | |||||
| Number of subjects with | |||||||||
| P. gingivalis | |||||||||
| Day 0 | 15 (93.7%) | 14 (87.5%) | 13 (86.6%) | 0.8590 | |||||
| Day 270 | 9 (56.2%) | 9 (56.3%) | 3 (20.0%)† | 0.0740 | |||||
| A. actinomycetemcomitans | |||||||||
| Day 0 | 3 (18.7%) | 3 (18.7%) | 0 (0%) | 0.2200 | |||||
| Day 270 | 1 (6.3%) | 6 (37.5%) | 5 (33.3%) | 0.0860 | |||||
| T. forsythia | |||||||||
| Day 0 | 16 (100%) | 16 (100%) | 15 (100%) | 1.0000 | |||||
| Day 270 | 12 (75.0%) | 11 (68.7%) | 10 (66.6%) | 0.9240 | |||||
Intra- group comparison by
*
Wilcoxon signed rank test and Mc Nemar test. p<0.05. Significant values were given in bold formatting. Inter-group comparison by
**
Kruskal Wallis test, ANOVA and Fisher's exact test. p<0.05