(Top panel) OS by landmark analysis of 2 years for patients who achieved CR after chemotherapy alone or after added HDT. Among 23 patients with CR without HDT, initial therapy had been dexamethasone (D) in 18, thalidomide-dexamethasone (TD) in 3 and bortezomib-thalidomide-dexamethasone (BTD) in 2; among 29 patients with intensive therapy of CR, initial therapy had been D in 14, TD in 10 and BTD in 5. (Middle panel) OS by landmark analysis of 2 years for 350 patients with PR who received HDT. Among 74 patients with CR, initial therapy had been D in 46, TD in 21 and BTD in 7; among 140 patients with PR, initial therapy had been D in 81, TD in 48 and BTD in 11; among 136 patients who achieved PR after chemotherapy alone, initial treatment had been D in 125, TD in 10 and BTD in 1. (Lower panel) OS by landmark analysis of 2 years for 150 patients with NR who received HDT. Among 12 patients with CR, initial therapy had been D in 8, and TD in 4; among 48 patients with PR, initial therapy had been D in 32, TD in 13 and BTD in 3; among 24 patients who remained NR despite HDT, initial therapy had been D in 18 and TD in 6; for 66 patients who remained NR after chemotherapy alone, initial treatment had been D in 64 and TD in 2.