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. Author manuscript; available in PMC: 2018 Jan 22.
Published in final edited form as: J Proteom Genom Res. 2017 Mar 4;2(1):1–12. doi: 10.14302/issn.2326-0793.jpgr-17-1447

Table 2.

Top pathway hits of the selected network genes

Ingenuity Canonical Pathways B-H p-value Genes
FXR/RXR Activation 4.68E-10 PPARG,PPARA,APOE,APOB,APOA1,SCARB1,APOC1,APOC2,HNF4A
Clathrin-mediated Endocytosis Signaling 7.76E-09 HSPA8,APOE,APOB,APOA1,F2R,GRB2,APOC1,APOC2,UBC
Telomerase Signaling 5.01E-08 TP53,MYC,RB1,GRB2,TERT,CDKN1A,EGFR
IL-12 Signaling and Production in Macrophages 3.39E-07 PPARG,APOE,APOB,APOA1,APOC1,APOC2,REL
Prostate Cancer Signaling 4.68E-07 TP53,RB1,AR,GRB2,CREB1,CDKN1A
ERK/MAPK Signaling 2.51E-06 PPARG,YWHAQ,MYC,GRB2,CREB1,YWHAZ,ESR1
Myc Mediated Apoptosis Signaling 2.88E-06 YWHAQ,TP53,MYC,GRB2,YWHAZ
LXR/RXR Activation 2.88E-06 APOE,APOB,APOA1,APOC1,APOA5,APOC2
Atherosclerosis Signaling 2.88E-06 APOE,APOB,APOA1,CXCL12,APOC1,APOC2
Estrogen-mediated S-phase Entry 2.88E-06 MYC,RB1,CDKN1A,ESR1