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. Author manuscript; available in PMC: 2018 Jul 17.
Published in final edited form as: Nature. 2018 Jan 17;553(7688):295–300. doi: 10.1038/nature25440

Figure 3. Protein-DNA contacts in the Pol III PIC.

Figure 3

a, TFIIIB encircles promoter DNA. Left: Cylinder representation of TFIIIB around the TATA box with DNA represented as surface (left) and electrostatic potential mapped onto the TFIIIB structure (right). b, The transcription bubble is stabilized by Brf1 cyclin I, the Pol III clamp, C34 WH2 and C82 WH4. The non-template DNA strand is stabilized by the C82 cleft loop and C34 WH2.