Table 1.
Current BCG vaccine manufacturers (March 2017).a
| Manufacturer | Country | Strain | Supplying beyond domestic market | PQ Status | Releasing NRA functionality | Vial size | Route of administration | Supplying in 2017 |
|---|---|---|---|---|---|---|---|---|
| ANLIS | Argentina | Pasteur 1173 P2 strain | N | N | N | 10ds/20ds | Unknown | Y |
| Fundação Ataulpho de Paiva | Brazil | Moreau, Rio strain | Y | N | Y | 10ds | Unknown | N |
| BulBio-NCIPDb | Bulgaria | Bulgarian substrain (Sofia) SL222 | Y | Y | Y | 10ds/20ds | Intradermal | Y |
| China National Biotec Group (Shanghai) | China | Chinese substrain Shanghai D2PB302 (derived from Danish strain 823) | Y | N | Y | 5ds | Intradermal | Y |
| China National Biotec Group (Chengdu) | China | Chinese substrain Shanghai D2PB302 (derived from Danish strain 823) | Y | N | Y | 5ds | Intradermal | Y |
| Shaanxi Pharmaceutical Holding Group | China | Chinese substrain Shanghai D2PB302 (derived from Danish strain 823) | N | N | Y | 20ds | Unknown | Y |
| AJ Biologics | Denmark | Danish 1331 strain | Y | Y | Y | 10ds/20ds | Intradermal | N |
| Serum Institute of India | India | Russian (Moscow) – 368 | Y | Y | Y | 10ds/20ds | Intradermal | Y |
| Green Signal Biopharma | India | Danish 1331 strain | Y | Y | Y | 20ds | Intradermal | Y |
| BCG Vaccine Laboratory, Chennai | India | Danish 1331 strain, Madras Working Seed Lot (MWSL) | Y | N | Y | 10ds/20ds | Intradermal | N |
| Taj Pharma Ltd | India | Russian (Moscow) – 368 | N | N | Y | 20ds | Unknown | Y |
| BioFarma | Indonesia | Pasteur 1173P strain | Y | N | Y | 5ds/10ds | Intradermal | Y |
| Pasteur Institute of Iran | Iran | Pasteur 1173P2 strain | N | N | Y | 20ds | Intradermal | Y |
| Japan BCG Laboratory (JBL) | Japan | Tokyo 172-1 strain | Y | Y | Y | 10ds/20ds | Intradermal/percutaneous (multipuncture device) | Y |
| Biomed Lublin | Poland | Moreau strain | Y | N | Y | 10ds | Intracutaneous | Y |
| Microgen | Russia | Russian (Moscow) – 368 | Y | N | Y | 10ds/20ds | Intradermal | Y |
| Inst. Of Virology, Vaccines and Sera Torlak | Serbia | Pasteur 1173P2 strain | Y | N | N | 10ds/20ds | Intradermal | Y |
| NIIDV | Taiwan | Tokyo 172 strain | N | N | Y | 20ds | Intradermal | Y |
| Queen Saovabha Mem. Inst (Thai Red Cross) | Thailand | Japanese strain | N | N | Y | 10ds | Intradermal | Y |
| Inst. Pasteur Tunis | Tunisia | Pasteur 1173P2 strain | N | N | Y | 20ds | Intradermal | Y |
| Merck & Co (former Organon) | United States | TICE strain | N | N | Y | 1ds | Percutaneous (multipuncture device) | Y |
| IVAC – Institute of Vaccines and Medical Biologicals | Vietnam | Pasteur 1173P2 strain | N | N | Y | 20ds | Unknown | Y |
a
Compiled with the help of PAHO Revolving Fund, International Federation of Pharmaceutical Manufacturers & Associations (IFPMA) and Developing Countries Vaccine Manufacturers Network (DCVMN), as well as through a review of published literature [12,28–33], UNICEF Supply Division market updates [13], and internal reports from the Bill & Melinda Gates Foundation (BMGF) and Clinton Health Access Initiative (CHAI).
b
BulBio vaccine is also distributed by InterVax.