Table 2. Summary of copy number variation (CNV) in each L. donovani strain*.
| WHO Code | No. complete gene deletions (CNV = 0) | No. haploid genes (CNV = 1) | No. polyploidy genes (CNV>2) |
Average polyploidy | Average CNV |
|---|---|---|---|---|---|
| MHOM/ET/2009/AM421 | 0 | 19 | 19 | 3.31 | 2.16 |
| MHOM/ET/2009/AM422 | 0 | 7 | 19 | 3.42 | 2.77 |
| MHOM/ET/2010/AM546 | 0 | 18 | 20 | 3.15 | 2.13 |
| MHOM/ET/2010/AM548 | 0 | 18 | 18 | 3.16 | 2.08 |
| MHOM/ET/2010/AM551 | 0 | 17 | 25 | 3.12 | 2.26 |
| MHOM/ET/2010/AM552 | 0 | 16 | 21 | 3.14 | 2.21 |
| MHOM/ET/2010/AM553 | 0 | 4 | 24 | 3 | 2.71 |
| MHOM/ET/2010/AM554 | 0 | 16 | 17 | 3.17 | 2.12 |
| MHOM/ET/2010/AM560# | 0 | 14 | 44 | 3.16 | 2.65 |
| MHOM/ET/2010/AM563 | 0 | 19 | 53 | 3.3 | 2.71 |
| MHOM/ET/2009/GR356# | 0 | 2 | 31 | 3.1 | 3.01 |
| MHOM/ET/2010/GR363sp# | 0 | 4 | 5 | 3.8 | 2.62 |
| MHOM/ET/2010/GR363sk# | 0 | 3 | 5 | 3.8 | 2.74 |
| MHOM/ET/2010/GR364sp# | 0 | 4 | 22 | 3.32 | 2.96 |
| MHOM/ET/2010/GR364sk# | 0 | 7 | 34 | 3.31 | 2.95 |
| MHOM/ET2010/GR379 | 0 | 3 | 16 | 3.25 | 2.90 |
| MHOM/ET/2010/GR383# | 0 | 5 | 74 | 4.51 | 4.23 |
| MHOM/ET/2009/LDS373bm | 2 | 10 | 158 | 3.04 | 2.88 |
| MHOM/ET/2009/LDS373sp | 0 | 2 | 18 | 3.38 | 3.15 |
| MHOM/SD/1998/S3570 | 0 | 4 | 27 | 3.77 | 3.42 |
*A summary of the absolute number of different genes showing CN≠2 over all isolates examined in this study e.g., complete gene deletion (CN = 0), deletion of one copy (CN = 1) or greater than two copies of a gene (CN>2). Isolates from southern Ethiopia (SE) have codes beginning with AMxxx, where xxx represents the strain number. Isolates from northern Ethiopia (NE) have codes beginning with either GRxxx or LDSxxx, where xxx represents the strain number.
#Multiple clones exist for the same patient strain, and the value given represents the average number of genes showing gene copy number different from CN = 2.