Fig 6. Muc1-Bi-1 and Muc1-Bi-2 mediate specific cytotoxic activities in a dose dependent manner.

Cytotoxicity assays were performed as described in the Materials and Method. Muc1-Bi-1 and Muc1-Bi-2 were incubated with different cell lines with or without the presence of NK cells (E:T ratio = 10:1). a). CHO, b). HT29, c). LS174T, d). SKOV3). The concentrations of Muc1-Bi-1 or Muc1-Bi-2 were ranging from 0.1 ng/ml to 10 μg/ml.