Skip to main content
. 2017 Dec 7;8(70):114506–114525. doi: 10.18632/oncotarget.23016

Figure 5. CAPE and CAPE-pNO2 inhibited inflammation through the Akt/NF-κB pathway in diabetic mice.

Figure 5

(A–G) The expressions of PI3K, p-PI3K, Akt, p-Akt, p-IκBα, IκBα and p65 in nuclear and cytoplasm were assessed by western blot. Data are expressed as mean ± SD, n ≥ 6. #p < 0.05 vs. control group; *p < 0.05 vs. diabetes group; +p < 0.05 vs. CAPE group; &p < 0.05 vs. Low-pNO2 group. Diabetes: the STZ-induced diabetic mice; CAPE: the STZ-induced diabetic mice treated with CAPE (20 μmol/kg/day); Low-pNO2: the STZ-induced diabetic mice treated with CAPE-pNO2 (20 μmol/kg/day); High-pNO2: the STZ-induced diabetic mice treated with CAPE-pNO2 (40 μmol/kg/day).