Table 1. Effects of CAPE and CAPE-pNO2 treatment on blood urea nitrogen, serum creatinine, 24 h albumin, triglyceride and cholesterol in diabetic mice.
| Control Group | Diabetes Group | Diabetes + Treatment Group | |||
|---|---|---|---|---|---|
| CAPE(20 μmol/kg) | CAPE-pNO2(20 μmol/kg) | CAPE-pNO2(40 μmol/kg) | |||
| sCr (μmol/L) | 46.26 ± 9.09 | 95.96 ± 2.74# | 59.73 ± 1.98* | 54.38 ± 2.04* | 43.42 ± 4.79*& |
| BUN (mmol/L) | 8.02 ± 0.42 | 15.16 ± 1.55# | 12.12 ± 0.24* | 11.12 ± 1.23* | 10.67 ± 0.98* |
| Alb (mg/24h) | 1.31 ± 0.03 | 18.19 ± 0.44# | 12.16 ± 0.53* | 10.15 ± 0.42*+ | 6.68 ± 0.31*& |
| TC (mmol/L) | 3.22 ± 0.11 | 4.44 ± 0.06# | 3.43 ± 0.20* | 3.32 ± 0.16* | 3.09 ± 0.05*& |
| TG (mmol/L) | 0.77 ± 0.02 | 2.73 ± 0.10# | 1.87 ± 0.39* | 1.73 ± 0.05*+ | 1.36 ± 0.03*& |
Data are expressed as mean ± SD, n ≥ 6. #p < 0.05 vs. control group; *p < 0.05 vs. diabetes group; +p < 0.05 vs. CAPE group; &p < 0.05 vs. Low-CAPE-pNO2 group.