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. 2017 Nov 29;8(70):114648–114662. doi: 10.18632/oncotarget.22754

Figure 2. Box plots of proportion of aDNAm’s.

Figure 2

Box plots showed the expected (line) and observed (box) aDNAm’s by functional genomic location (A) CpGIslands/shores/shelf/opensea (B) and enhancer (C) Pink and blue boxes represent gain and loss of methylation, respectively. A proportion was tested (Chi-Squre) for a difference across regions between gain and loss of methylation (P-value in the box) and for a difference of gain/loss methylation compared to the expected aDNAm’s (P- value on the topt of box plot).