Figure 4. DNMT3A protein expression patterns by immunohistochemistry in histologically normal breast tissues (A) and correlations between age-related DNA methylation and gene expression (B).

(A) Low expression (upper) and high expression (lower) are shown in 10X, 20X, and 40X magnification. (B) Spearman coefficient (r) and P-values are presented. The x- and y- axis indicate the beta-value and intensity of corresponding transcript, respectively. Gene names and functional location of aDNAm’s are shown.