Table 2. Microarray analysis revealed 17 differentially expressed miRNAs over 2-fold in different EGFR status.
Signal intensity (Global normalization, ratio) | ||||
---|---|---|---|---|
miRNA | EGFR-wt | EGFR-mut | origin | wt/mut |
miR-16-5p | 10.20 | 140.30 | plasma | 0.07 |
miR-23a-3p | 12.90 | 83.90 | plasma | 0.15 |
miR-92b-3p | 41.60 | 166.70 | plasma | 0.25 |
miR-103a-3p | ND | 47.30 | plasma | - |
miR-122-5p | 11.60 | 110.20 | plasma | 0.11 |
miR-192-5p | 140.20 | 14.40 | tissue | 9.74 |
miR-194-5p | 222.90 | 2.90 | tissue | 76.86 |
miR-223-3p | ND | 80.70 | plasma | - |
miR-346 | 21.40 | 5.10 | plasma | 4.20 |
miR-451a | 78.50 | 749.70 | plasma | 0.10 |
miR-619-5p | 142.60 | 370.90 | plasma | 0.38 |
miR-1246 | 67.50 | 623.40 | plasma | 0.11 |
miR-1290 | 9.50 | 124.10 | plasma | 0.08 |
miR-4704-3p | 48.40 | ND | plasma | - |
miR-4732-5p | 30.80 | 107.50 | plasma | 0.29 |
miR-6765-3p | 140.50 | 57.20 | plasma | 2.46 |
miR-6778-5p | 75.50 | 350.40 | plasma | 0.22 |