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. 2017 Dec 1;8(70):114736–114745. doi: 10.18632/oncotarget.22827

Figure 2. HSD17B4 exerts tumor suppressive effect in ACC cells NCI-H295R and SW13 showing.

Figure 2

(A) constitutive HSD17B4 level; (B) robust knockdown (KD) of HSD17B4 using shRNAs in both cell lines and (C) robust upregulation of HSD17B4 in both cell lines; HSD17B4-KD and overexpression in NCI-H295 and SW13 cells effecting on (D) proliferation, (E) cell cycle and (F) cell apoptosis, respectively (**P < 0.01, n = 3).