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. 2017 Oct 30;8(70):114829–114838. doi: 10.18632/oncotarget.22162

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Copyright: © 2017 Liu et al.

This article is distributed under the terms of the Creative Commons Attribution License (CC-BY), which permits unrestricted use and redistribution provided that the original author and source are credited.

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(A) In 52 cases of osteosarcoma patients, circ-NT5C2 was significantly up-regulated in osteosarcoma tissue compared to adjacent non-tumor tissue. (B) Circ-NT5C2 was significantly up-regulated in osteosarcoma tissue. (C) Circ-NT5C2 levels were up-regulated in 36.5% (19/52) of osteosarcoma tissue samples. (D) Receiver operating characteristic (ROC) curve showed the diagnostic value of circ-NT5C2 in osteosarcoma tissue samples. The AUC (area under the curve) was 0.753. Data were expressed as mean ± SD. ^**P<0.01 represents statistically difference.